Coronary disease THE PATHOPHYSIOLOGY OF MYOCARDIAL ISCHAEMIA
نویسنده
چکیده
Correspondence to: Professor David C Crossman, Cardiovascular Research Unit, Division of Clinical Sciences (North), Clinical Sciences Centre, Herries Road, Northern General Hospital, Sheffield S5 7AU, UK; d.c.crossman@ sheffield.ac.uk _________________________ M yocardial ischaemia is responsible for angina, unstable angina, and, less commonly, shortness of breath secondary to ischaemic left ventricular dysfunction (angina equivalent) as well as cardiac arrhythmias. This article will deal with the mechanisms of myocardial ischaemia likely to be encountered in patients presenting with the chronic coronary insufficiency and stable symptoms of angina. It will not deal with the vessel wall based mechanisms of unstable or acute coronary syndromes which are covered elsewhere in this series.
منابع مشابه
Stable coronary syndromes: pathophysiology, diagnostic advances and therapeutic need
The diagnostic management of patients with angina pectoris typically centres on the detection of obstructive epicardial CAD, which aligns with evidence-based treatment options that include medical therapy and myocardial revascularisation. This clinical paradigm fails to account for the considerable proportion (approximately one-third) of patients with angina in whom obstructive CAD is excluded....
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